Opportunity Information: Apply for CDC RFA CK 16 005
This CDC funding opportunity (CDC RFA CK 16-005) supports a research project focused on how well non-pharmaceutical interventions (NPIs) reduce flu spread in real-world school settings. The central goal is to measure the impact of social distancing approaches, used either by themselves or paired with stronger personal hygiene (like hand hygiene) and/or environmental hygiene (like cleaning and disinfection practices), on two key outcomes: influenza-like illness (ILI) and lab-confirmed influenza. The target population is K-12 students, with an added emphasis on whether changes in illness patterns in schools also show up in the surrounding communities, which matters because schools can act as amplifiers of respiratory disease transmission.
Applicants are expected to design and carry out a cluster randomized controlled trial, meaning the intervention is assigned at the group level rather than the individual level. In practice, that usually means randomizing by school, grade, classroom, or another naturally occurring unit to compare different strategies under similar conditions. The trial design requirement signals that CDC is looking for stronger causal evidence than what can be obtained from simple before-and-after comparisons or observational studies. The interventions under study are non-pharmaceutical, so the focus is on behavioral and environmental measures rather than vaccines or antiviral medications, and the evaluation is expected to track both syndromic outcomes (ILI, typically defined by a set of symptoms) and laboratory outcomes (confirmed influenza via testing), which helps distinguish true influenza from other respiratory viruses that can look similar clinically.
The funding instrument is a cooperative agreement, not a standard grant. That generally indicates substantial involvement from the CDC during the project period, such as collaboration on study design elements, outcome definitions, monitoring plans, and possibly harmonization of data collection to ensure the results are interpretable and useful for public health decision-making. The award ceiling listed is $500,000, and the CDC anticipated making two awards. The opportunity falls under CFDA 93.084, within the health funding activity category, and is categorized as discretionary funding.
Eligibility is broad and intentionally inclusive, spanning many types of organizations that could realistically partner with school systems and run a field trial. Eligible applicants include state, county, and city or township governments; special district governments; and independent school districts. Higher education institutions are eligible, including public/state-controlled and private institutions, and the CDC explicitly encourages applications from certain categories of institutions such as Hispanic-serving institutions, Historically Black Colleges and Universities (HBCUs), Tribally Controlled Colleges and Universities (TCCUs), and Alaska Native and Native Hawaiian Serving Institutions. Various nonprofit organizations may apply, whether or not they have 501(c)(3) status (as long as they are not institutions of higher education when applying under the nonprofit category). Tribal governments (federally recognized) and other tribal organizations are eligible, as are public housing authorities/Indian housing authorities. The eligibility list also includes for-profit organizations (other than small businesses) and small businesses, along with other entities such as faith-based or community-based organizations, regional organizations, U.S. territories or possessions, eligible federal agencies, and Federally Funded Research and Development Centers (FFRDCs), which are specialized research entities set up to meet long-term federal research and development needs.
Key administrative details in the listing show the opportunity was created on 2015-11-13, with an original closing date of 2016-01-15. Overall, the opportunity is aimed at generating practical, high-quality evidence on how combinations of social distancing and hygiene measures perform in K-12 schools, using a rigorous cluster randomized trial approach, and translating those findings into clearer guidance about reducing ILI and confirmed influenza in both schools and nearby communities.Apply for CDC RFA CK 16 005
- The Centers for Disease Control and Prevention in the health sector is offering a public funding opportunity titled "Evaluating the Impact of Non-pharmaceutical Measures on the Incidence of Influenza-like Illness (ILI) among" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.084.
- This funding opportunity was created on 2015-11-13.
- Applicants must submit their applications by 2016-01-15. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Each selected applicant is eligible to receive up to $500,000.00 in funding.
- The number of recipients for this funding is limited to 2 candidate(s).
- Eligible applicants include: Others.
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Applicants who have applied for this opportunity (CDC RFA CK 16 005) also looked into and applied for these:
| Funding Opportunity |
|---|
| National Centers on Health Promotion for People with Disabilities Apply for CDC RFA DD16 1602 Funding Number: CDC RFA DD16 1602 Agency: Centers for Disease Control - NCBDDD Category: Health Funding Amount: $4,500,000 |
| Enhanced Surveillance for New Vaccine Preventable Diseases Apply for RFA IP 16 004 Funding Number: RFA IP 16 004 Agency: Centers for Disease Control and Prevention - ERA Category: Health Funding Amount: $1,000,000 |
| Connecting Kids to Coverage Outreach and Enrollment Cooperative Agreements Apply for CMS 1Z0 16 001 Funding Number: CMS 1Z0 16 001 Agency: Centers for Medicare Medicaid Services Category: Health Funding Amount: $1,000,000 |
| National Collaboration to Support Health, Wellness and Academic Success of School-Age Children Apply for CDC RFA DP16 1601 Funding Number: CDC RFA DP16 1601 Agency: Centers for Disease Control - NCCDPHP Category: Health Funding Amount: $600,000 |
| Support of Global Polio Eradication Initiative (GPEI) using Integrated Modeling Apply for CDC RFA GH16 1602 Funding Number: CDC RFA GH16 1602 Agency: Centers for Disease Control - CGH Category: Health Funding Amount: Case Dependent |
| Childhood Obesity Research Demonstration 2.0 Apply for RFA DP 16 004 Funding Number: RFA DP 16 004 Agency: Centers for Disease Control and Prevention - ERA Category: Health Funding Amount: $1,750,000 |
| Spatially Scalable Integrated Tick Vector/Rodent Reservoir Management to Reduce Human Risk of Exposure to Ixodes scapularis Ticks Infected with Lyme Disease Spirochetes Apply for RFA CK 16 002 Funding Number: RFA CK 16 002 Agency: Centers for Disease Control and Prevention - ERA Category: Health Funding Amount: $300,000 |
| Research Grants for Preventing Violence and Violence Related Injury (R01) Apply for RFA CE 16 001 Funding Number: RFA CE 16 001 Agency: Centers for Disease Control and Prevention - ERA Category: Health Funding Amount: $350,000 |
| Improving Epilepsy Programs, Services, and Outcomes through National Partnerships Apply for CDC RFA DP16 1602 Funding Number: CDC RFA DP16 1602 Agency: Centers for Disease Control - NCCDPHP Category: Health Funding Amount: $4,000,000 |
| Reinforcing Capacity at Two Centers of Excellence to Sustain the Delivery of Comprehensive HIV Clinical Services in Haiti under the President’s Emergency Plan for AIDS Relief (PEPFAR) Apply for CDC RFA GH16 1680 Funding Number: CDC RFA GH16 1680 Agency: Centers for Disease Control - CGH Category: Health Funding Amount: $3,000,000 |
| Strengthening Health Management Information Systems, Data Use and Data Quality in the Republic of Zimbabwe under the President’s Emergency Plan for AIDS Relief (PEPFAR) Apply for CDC RFA GH16 1674 Funding Number: CDC RFA GH16 1674 Agency: Centers for Disease Control - CGH Category: Health Funding Amount: $1,500,000 |
| Centers for Autism and Developmental Disabilities Research and Epidemiology (CADDRE): Study to Explore Early Development (SEED) 3 Apply for RFA DD 16 001 Funding Number: RFA DD 16 001 Agency: Centers for Disease Control and Prevention - ERA Category: Health Funding Amount: $800,000 |
| Technical Assistance to Host Country Public Health Institutions in Tanzania to Lead HIV Response and Develop and Sustain Systems Required to Achieve and Sustain HIV Epidemic Control under the President's Emergency Plan for AIDS Relief (PEPFAR) Apply for CDC RFA GH16 1650 Funding Number: CDC RFA GH16 1650 Agency: Centers for Disease Control - CGH Category: Health Funding Amount: $1,159,375 |
| Building Capacity to Deliver High Quality HIV Prevention, Care and Treatment Services for Key Populations and People Living with HIV in the Caribbean Region under the President’s Emergency Plan for AIDS Relief (PEPFAR) Apply for CDC RFA GH16 1607 Funding Number: CDC RFA GH16 1607 Agency: Centers for Disease Control - CGH Category: Health Funding Amount: $1,036,000 |
| HIV Surveillance for Epidemic Control in Malawi under the President’s Emergency Plan for AIDS Relief (PEPFAR) Apply for CDC RFA GH16 1629 Funding Number: CDC RFA GH16 1629 Agency: Centers for Disease Control - CGH Category: Health Funding Amount: $700,000 |
| Assisting the Ministry of Health and Social Services (MOHSS) in Providing Critical Human Resources for Health to Achieve HIV Epidemic Control in Namibia under the President’s Emergency Plan for AIDS Relief (PEPFAR) Apply for CDC RFA GH16 1640 Funding Number: CDC RFA GH16 1640 Agency: Centers for Disease Control - CGH Category: Health Funding Amount: $8,867,471 |
| Prevention of Healthcare-Associated Tuberculosis Infection in Zimbabwe under the President’s Emergency Plan for AIDS Relief (PEPFAR) Apply for CDC RFA GH16 1673 Funding Number: CDC RFA GH16 1673 Agency: Centers for Disease Control - CGH Category: Health Funding Amount: $1,500,000 |
| Strengthening the HIV Services Quality Improvement and Quality Management Systems of the Ethiopian Federal Ministry of Health, Regional Health Bureaus, and Public Health Facilities under the President’s Emergency Plan for AIDS Relief (PEPFAR) Apply for CDC RFA GH16 1614 Funding Number: CDC RFA GH16 1614 Agency: Centers for Disease Control - CGH Category: Health Funding Amount: $1,000,000 |
| Supporting the Implementation and Expansion of High Quality, Sustainable and Comprehensive HIV Prevention, Care and Treatment Programs in the Central Region and Laikipia County of the Republic of Kenya under the President’s Emergency Plan for A Apply for CDC RFA GH16 1700 Funding Number: CDC RFA GH16 1700 Agency: Centers for Disease Control - CGH Category: Health Funding Amount: $10,000,000 |
| Supporting Implementation of Comprehensive HIV Prevention, Care and Treatment Programs in Bomu Hospital Affiliated Sites, Coptic Hospitals, and Faith-Based Sites in the Eastern Slums of Nairobi, Kenya under the President’s Emergency Plan for AI Apply for CDC RFA GH16 1690 Funding Number: CDC RFA GH16 1690 Agency: Centers for Disease Control - CGH Category: Health Funding Amount: $18,500,000 |
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