Opportunity Information: Apply for PD 22 7334
The National Science Foundation (NSF) Mathematical Biology Program (Funding Opportunity Number PD 22-7334) funds research grants that sit at the intersection of applied or computational mathematics and the biological sciences. The core expectation is that proposed work is not just "math applied to biology" or "biology with some modeling," but a tightly integrated project where the mathematical ideas and the biological questions genuinely drive each other. Competitive proposals are expected to show clear mathematical innovation (new theory, new methods, or a meaningful advance in existing mathematical frameworks), strong biological relevance and significance (a real biological problem with clear importance), and a convincing plan for integration between the two disciplines.
The program is broad in the kinds of mathematical approaches it welcomes, including areas that may traditionally be housed elsewhere within NSF's Division of Mathematical Sciences. Examples explicitly noted include topology, probability, statistics, and computational mathematics, among others, as long as the work is meaningfully connected to biological science and the proposal makes the case for why these tools are needed and what new insight they enable. Because many projects naturally overlap multiple NSF programs, investigators are encouraged to communicate early with the relevant program officers. If a project could reasonably be reviewed by more than one program, NSF recommends contacting the program officers for each potentially relevant program to decide where to submit and to help coordinate the review process. The Mathematical Biology Program also regularly pursues joint reviews with programs in the Biological Sciences and Engineering directorates, which can be helpful for proposals that genuinely span disciplinary boundaries.
The opportunity is listed as a discretionary grant in the Science and Technology and other Research and Development category (CFDA 47.049). Eligibility is described as unrestricted, meaning it is broadly open to different entity types, subject to any specific eligibility clarifications that may appear in the full solicitation or related NSF policy documents. Proposals are accepted on an ongoing basis (no single deadline listed), and NSF anticipates making around 30 awards. The award ceiling is shown as 0, which typically signals that a fixed maximum is not specified in the listing itself; applicants generally need to rely on NSF guidance, norms for the program, and conversations with program staff to shape an appropriate budget.
The description also highlights several submission pathways and special cases that come with extra requirements. Faculty at Research in Undergraduate Institutions (RUI) can apply, but they are expected to follow the separate RUI solicitation because formatting and preparation rules can differ from the standard NSF Proposal and Award Policies and Procedures Guide (PAPPG). For EAGER (early concept, exploratory) and RAPID (rapid response) proposals, prior contact with the cognizant program directors is required before submission, reflecting NSF's normal practice that these mechanisms need advance discussion and approval. Similarly, principal investigators considering requests for award supplements are encouraged to contact the program director before submitting the supplement request, and to consult the PAPPG for procedural details.
Finally, the program notes conference and workshop support as another activity area, with a reminder to consult the NSF solicitation "Conferences and Workshops in the Mathematical Sciences" for specific content expectations. Timing matters for these proposals: events held in the United States should be proposed about 8 months in advance, while requests to support group travel to meetings outside the United States should be submitted about 12 months ahead of the meeting date. Overall, the opportunity is designed for researchers who can demonstrate both cutting-edge mathematical development and a clear, high-impact biological application, and who are willing to coordinate across NSF programs when the project spans multiple review communities.Apply for PD 22 7334
- The National Science Foundation in the science and technology and other research and development sector is offering a public funding opportunity titled "Mathematical Biology" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 47.049.
- This funding opportunity was created on Jul 11, 2022.
- Applicants must submit their applications by Proposals accepted anytime. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- The number of recipients for this funding is limited to 30 candidate(s).
- Eligible applicants include: Unrestricted (i.e., open to any type of entity above), subject to any clarification in text field entitled Additional Information on Eligibility.
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